PRODH and diffuse large B-cell lymphoma: LOC283177 was therefore the most significantly associated gene with DLBCL (PFDR = 2.77×10−2), followed by DGCR6 and PRODH, both located on chromosome 22q11.21 and duplicated in 10 (4.1%) of the DLBCL cases, although the association for these genes was not significant after correction for multiple testing.