S1P has been shown to be exported from mast cells via ABCC1 (also known as multidrug resistant protein 1; MRP1) [9], from astrocytes via ABCA1 [44], from endothelial cells via ABCA1 and ABCC1 [45], and from thyroid carcinoma cells via ABCC1 [46]. This evidence concerns the gene ABCC1 and thyroid gland carcinoma.