In this regard, future research is needed to elucidate if: 1) decrements in Akirin-1/Mighty mRNA expression accompany and/or causal to muscle wasting conditions such as sarcopenia, cachexia, and disuse atrophy; and 2) if each of the anabolic ingredients studied herein mitigate these conditions through Akirin-1/Mighty gene expression changes. Here, AKIRIN1 is linked to sarcopenia.