A significantly higher percentage of CD4+Foxp3+ cells from asthma patients compared with healthy subjects expressed IFN-γ [42.6% (25.4–71.2%) vs 29.1% (16.2–44.4%); Figure 1B; P = 0.01], IL-4 [48.8% (13.4–77.4%) vs 26.3% (16.7–43.6%); Figure 1C; P = 0.004] and CD25 [51.3% (11.9–88.1%) vs 35.1% (13.2–72.5%); Figure 1D; P = 0.04). The gene discussed is CD4; the disease is asthma.