Similarly, increased expression of inflammatory mediators is also found in PD animal models [51, 80, 86] and in postmortem PD brains [87, 88], including proinflammatory cytokines, such as IFN-γ, IL-1β, TNF, IL-2, and IL-6, released by microglia [89–91]. Here, IL1B is linked to Parkinson disease.