Our results indicated that IL-6-634 polymorphism was associated with the risk of lung cancer risk in female non-smokers.Individuals with both IL-6-634 CG or GG genotype and exposure to cooking oil fumes had a higher risk of lung cancer.Also individuals with both IL-6-634 CG or GG genotype and history of tuberculosis had an elevated risk of lung cancer. Here, IL6 is linked to lung carcinoma.