Of them, 14 subjects diagnosed with dementia agreed to undergo lumbar puncture for the measurement of specific proteins levels in the CSF (Aβ42, tau, and P-tau) and 20 patients (19 subjects with a core and/or suggestive clinical DLB feature) fulfilled the criteria for DLB and were designated as MCI-DLB (i.e., former MCI subjects who converted to DLB). This evidence concerns the gene MAPT and Lewy body dementia.