In the study by Kotani et al. control subjects had an IL-8 concentration of 18 μg/L (7 to 24 μg/L) in the CSF compared to 81 μg/L (57 to 380 μg/L) in patients with herpes zoster during rash and after rash healing (44 μg/L, 28 to 101 μg/L). This evidence concerns the gene CXCL8 and herpes zoster.