SOX2 and neoplasm: In particular, we demonstrated in our cohort that SOX2 expression correlated with a higher risk of tumor recurrence (p=0.017) and with a shorter disease-free survival compared to SOX2 tumors (median: 34.9 months; 95% CI: 7.5-62.2 vs. median: 60.3 months; 95% CI: 32.6-88.1, respectively).