XIAP and cancer: Therefore, we also examine the effect of NSC745885 on the XIAP gene and protein expression in oral cancer cells, we treated the SAS cancer cells with different concentrations (0 μM, 0.5 μM, 1.0 μM, 1.5 μM, and 2.0 μM) for 24 hours, and then determined their change in gene expression by using the Q-PCR.