CCN2 and hepatocellular carcinoma: Among the 314 HCC patients of cohort 1, DFS rate was significantly lower in HCC patients expressing CCN2, compared to those that did not (P = 0.005, Figure 4A); EMA and FAP expression was not associated with patient outcomes in this cohort (P = 0.362 and P = 0.287, respectively) (Figure 4.