TLR2 and bacterial infectious disease: Footrot is a mixed bacterial infection and, therefore, the TLRs likely to be involved in their recognition are TLR2, TLR2/TLR1 and TLR2/TLR6 heterodimers (which recognise bacterial lipoproteins, lipoteichoic acid and atypical LPS, respectively), TLR4 (which is activated by bacterial LPS), TLR5 (which recognises bacterial flagellin) and TLR9 (which recognises bacterial DNA).