Immunohistochemical stains were done with the following markers: Cytokeratin (CK) 7, CK20, Cell adhesion molecule (CAM) 5.2, p63, Uroplakin III, Vimentin, E-cadherin, p53, Cluster of differentiation (CD) 10, Paired box protein (PAX) 8, Renal cell carcinoma (RCC), CD117, Placental alkaline phosphatase (PLAP), S-100 protein, Human melanoma black (HMB) 45, Prostate Specific Antigen (PSA), Cancer Antigen 125 (CA-125), and Ki-67. The gene discussed is MUC16; the disease is hereditary clear cell renal cell carcinoma.