Some signaling pathways were predominantly affected within a particular cell line, e.g., pathways related to TP53 or NFκB in prostate cells, the epidermal growth factor (EGF), the activator protein 1 (AP1), and immune response related pathways in ovarian cancer, while fatty acids metabolism and response to exogenous chemicals associated pathway were affected in melanoma cells (marked with colors in Table S7). The gene discussed is NFKB1; the disease is ovarian cancer.