Upon infection with ECTV or VACV, p65 was retained in the cytoplasm following treatment with TNFα or IL-1β, indicating that ECTV could inhibit NF-κB despite the lack of orthologs of M2, K7, B14, A49, and A52 (Fig. 2A panels g–l and D panels s–x). This evidence concerns the gene TNF and infection.