By use of a chemotaxis assay employing the CCL3-responding murine T cell lymphoma cell line Esb-MP, we observed that the cells migrated in response to CCL3-gp120 whereas no specific migration was observed towards the non-targeted vaccine CCL3C11S-gp120, confirming the functional activity of the CCL3-moiety (Fig. 2D). This evidence concerns the gene ITIH4 and T-cell non-Hodgkin lymphoma.