The subjects who were heterozygous or homozygous for the minor allele of this MUC5B polymorphism rs35705950 have a significantly increased risk for IPF (OR = 6.8 and 20.8) and for sporadic IPF (OR = 9.0 and 21.8), respectively [14]. The gene discussed is MUC5B; the disease is idiopathic pulmonary fibrosis.