α-Catenin interacts with the cadherins indirectly via interactions with β-catenin or plakoglobin, and links the cadherin–catenin complex to the actin cytoskeleton through interactions with α-actinin, vinculin, formin, EPLIN (epithelial protein lost in neoplasm), and actin filaments [1]. This evidence concerns the gene CDH17 and neoplasm.