RT-qPCR analysis revealed that the mean RQ values of B7-H3 and B7-H1 in the glioma tissue of the patients with LGG were 0.610±0.583 and 0.849±0.397, respectively, and in the patients with HGG were 7.287±5.207 and 3.813±3.350, respectively (Fig. 2A and B and Table II). The gene discussed is CD274; the disease is central nervous system cancer.