Previous studies have shown that TCAB1 is a constitutive component of CBs, which has been detected within CBs in a panel of cancer and primary cell lines, including: U2OS, osteosarcoma; H1299, lung cancer; HCT116, colon cancer; HeLa-PV, cervical cancer; HEK293, embryonic kidney cancer; MCF-7, mammary epithelial cells; and HDF, human diploid fibroblasts. This evidence concerns the gene WRAP53 and cancer.