These clinical features include unique hemorrhagic syndrome, disseminated intravascular coagulation (DIC) and association with the translocation between chromosomes 15 and 17, resulting in the formation of two reciprocal fusion genes; promyelocytic leukemia (PML)/retinoic acid α-receptor (RARA) on chromosome 15 and RARA/PML on chromosome 17. The gene discussed is PML; the disease is Disseminated intravascular coagulation.