The NUP214-ABL1 fusion is a late event and not the only aberration in T-ALL, often in combination with the deletion of the important tumor suppressor genes CDKN2A and PTPN2 (34) and the overexpression of TLX1 or TLX3 (27,32), increasing the risk of a poor survival time (28). This evidence concerns the gene NUP214 and acute lymphoblastic leukemia.