The data revealed that the expression levels of the EBP50 protein were significantly higher in EBP50-PANC-1 and EBP50-SW1990 cells than those in the PANC-1/HA-PANC-1 and SW1990/HA-SW1990 cells, respectively (Fig. 1), thus indicating that the EBP50 protein was upregulated in the two PC cell lines. The gene discussed is NHERF1; the disease is pachyonychia congenita.