As shown in Table I, 53.9 and 51.3% of LSCC samples were positive for ARTN and GFRα1, respectively, whilst only 26.9% of normal squamous epithelium from patients with polyp were positive for ARTN and GFRα1 (P=0.015 and P=0.031, respectively). The gene discussed is GFRA1; the disease is polyp.