CD8A and disease arising from reactivation of latent virus: Similarly, during latent infection in BALB/c mice, when H-2Ld is expressed only in hematopoietic cells, H-2Ld-restricted IE1-specific CD8 T cells fail to undergo inflation, in contrast to H-2Dd-restricted m164-specific CD8 T cells (Seckert et al., 2011).