These factors, which can promote the formation of amylin amyloids, include the following: (1) insulin resistance like hyperglycemia (de Koning et al., 1994), (2) the ob gene introduction (Hoppener et al., 1999), or (3) glycosylation of amylin (Kapurniotu et al., 1998). The gene discussed is IAPP; the disease is Hyperglycemia.