There was no significant difference between a-PRL and nonpregnant active SLE patients in terms of the levels of erythrocyte sedimentation rate (ESR) or complements (C3, C4, CH50), or the proportion of patients with positive anti-dsDNA, anti-SSA/anti-Ro, anti-SSB/anti-La, anti-ribosomal P, anti-U1RNP, anti-Sm, anticardiolipin (ACL), or anti-beta-2 glycoprotein 1(anti-β2GP1) antibodies (p>0.05). This evidence concerns the gene C4A and systemic lupus erythematosus.