PARL and type 2 diabetes mellitus: The aims of this study are: (1) to assess if the previously reported PARL missense Val262Leu polymorphism (not genotyped on commercial arrays) is associated with population fasting plasma insulin levels and (2) to conduct a comprehensive T2D candidate gene association and functional expression study of the linkage disequilibrium (LD) region (approximately 185,000–185,250 kb, Build 36) that includes PARL and neighbouring ABCC5.