APOA1 and hepatocellular carcinoma: In a previous study, we explored the pathogenesis of CHB by screening the differential expression genes between the hepatocellular carcinoma cell line HepG2 and HepG2.2.15 cell lines (integrated the HBV genome) by gene chip and found that the expression of ApoA1 in HepG2.2.15 was significantly decreased [2].