P4HA1 and Familial prostate cancer: qPCR analysis in prostate cancer cell lines showed that benign prostate epithelial cell line PrEC expressed greater amounts of miR-124 and lower P4HA1 levels in contrast to aggressive prostate cancer cell lines DU145 and PC3 that express lower miR-124 and higher P4HA1 levels (Supplementary Fig. S4C).