1)Breast cancer: ER stress/ERK and reactive oxygen species (ROS) pathways2)Prostate cancer: ERK1/2 and AKT pathways3)Lung cancer: up-regulation of TIMP-1 Cox-2 and PPAR-γ regulation4)Cervical cancer: Up-regulation of TIMP1. The gene discussed is MAPK3; the disease is cervical cancer.