To further validate the significance of the individual gene sets (ERG-fusion, ESC, ESC_New, MYC and MYC_New) in separating PCa samples with poor and good prognosis, we compared the individual gene set scores for these five signatures between the following sample sets: i) The 54 cancer samples with bad prognosis from cluster 1 and highlighted in Figure 2, ii) The 21 cancer samples initially assigned with good prognosis (p < 0.25, Table 1A) and iii) The 40 normal samples. This evidence concerns the gene ERG and cancer.