We analyzed the clinical correlation of CXCR4 expression with tumor size, lesion type (proliferative, ulceroproliferative, infiltrative, ulceroinfiltrative, and ulcerative), tumor stage (IIA, IB, IIB, and IIIB), and grade (poorly differentiated and undifferentiated), but we did not find significant difference among the groups. The gene discussed is CXCR4; the disease is neoplasm.