Similarly, in the study done by Celik et al in Turkey, in patients suffering from PCOS, there was no significant difference in insulin resistance parameters and fasting insulin levels between two groups of SCH and euthyroidism; however, the PCOS+SCH group had higher levels of fasting insulin as well as greater insulin resistance compared to normal people and those with euthyroidism (14). This evidence concerns the gene INS and polycystic ovary syndrome.