ENG and colitis: Figure 1(b) (top panels) shows the extensive epithelial ulceration and immune cell infiltration observed in histological colonic sections from both groups of mice at day 9 of colitis. In Eng+/− mice, colonic inflammation and ulcerated epithelium persist while resolution of epithelial damage and inflammation is observed in Eng+/+ mice, as shown by day 19 representative histological colonic sections (Figure 1(b), lower panels).