Figure 1(c) showed abundant RAGE labeling observed in both odontoblastic and subodontoblastic cell layers (A and B), as well as in odontoblast processes in tubules of the predentin (A and B, arrow), stromal pulp fibroblasts-like cells (C, arrowhead), and endothelial-like cell lining in the pulpitis tissues (A and B). This evidence concerns the gene AGER and pulpitis.