Mean basal release of PGD2 from PBLs was indeed markedly enhanced (6.6-fold) in patients with MCAD (946 ± 302.2 pg/ml; P < 0.001), as compared to healthy individuals (142 ± 47.8 pg/ml) (Figure 2A). The gene discussed is PTGDS; the disease is medium chain acyl-CoA dehydrogenase deficiency.