Furthermore, we assessed which of the 13 variables studied (age, gender, location of the primary tumor, histological type, tumor size, lymphatic invasion, venous invasion, pT and pN category, KCC3 score in MT, KCC3 score in CN and CN/MT, and KCC3 expression in the invasive front) influenced survival following curative resection of esophageal cancer. This evidence concerns the gene SLC12A6 and neoplasm.