Adult adrenocortical tumors were classified according to the Weiss criteria and included 23 adrenocortical adenomas (Weiss score < 3) and 16 carcinomas (Weiss score ≥ 3). IGF1R expression was previously studied in 45 patients (24 children/adolescents and 21 adults) using real time PCR [10], and the overexpression of this receptor was observed in 17 children and 5 adults [10]. This evidence concerns the gene IGF1R and adrenal cortex neoplasm.