Treatment with DGBX in early diabetic atherosclerosis rats resulted in significant inhibition of mRNAs expression of monocyte chemoattractant protein-1 (MCP-1), intercellular adhesion molecule-1 (ICAM-1), and CD36 (a FA translocase that mediates oxidized LDL uptake) in aorta so it helped the prevention of diabetic atherosclerosis. Here, ICAM1 is linked to atherosclerosis.