TMEM18 and obesity due to melanocortin 4 receptor deficiency: In addition, the genes having high scores of association with obesity are fat mass and obesity associated, catenin β-like 1, v-maf musculoaponeurotic fibrosarcoma oncogene 7 homolog, transmembrane protein 18, phosphodiesterase related, Niemann-Pick disease type C1, prolactin, and obesity candidate gene G protein β3 [12–14].