IL17A and psoriasis: In the immune-mediated condition psoriasis, using secukinumab (anti IL-17A monoclonal antibody), ixekizumab (anti IL-17 monoclonal antibody), and even an antibody against the receptor itself brodalumab (IL-17RA monoclonal antibody) has been shown to be effective in inducing and maintaining a remittance state in patients with moderate to severe plaques [129–131].