Tumour eradications, via a direct cytotoxic effect of Th17 cells, have been shown to exist via the expression of IFN-γ; although this effect was similar to Th1 effector cells in relying on IFN-γ in immune-resistance against tumours, the effect was significantly greater than that produced by the Th1 cells [114]. The gene discussed is IFNG; the disease is neoplasm.