The intensities of the anti-CgA immunoreactivity were 122.2±1.4, 126.0±0.8, 125.7±0.9, 124.7±3.7 and 127.0±1.4, in the controls and the IBS-total, IBS-D, IBS-M and IBS-C patients, respectively. This evidence concerns the gene CGA and irritable bowel syndrome.