For instance, BAC mice overexpressing human G2019S LRRK2 showed faster walking speed (and anxiety-like behavior) in the open field (Melrose et al., 2010) whereas human G2019S overexpressors under the Thy1 (Herzig et al., 2012) or the TetO CaMKII (Lin et al., 2009) promoters showed transient improvement in rotarod performance (Herzig et al., 2012) or increased exploratory behavior (Lin et al., 2009). The gene discussed is CAMK2G; the disease is Anxiety.