The expression of SKP2 (Z = -2.450, P = 0.014), cyclin E (Z = -2.068, P = 0.039), and stathmin (Z = -0.295, P = 0.768) was higher in primary low-grade ovarian carcinoma without metastasis than in borderline serous cystadenoma. The gene discussed is SKP2; the disease is ovarian carcinoma.