However, considering that DISC1 interacts with a complex formed by related molecules (including 14-3-3epsilon) during processes involved in neuronal development, such as axonal elongation [13], the present results raise the possibility that the genetic variation of DISC1-interacting molecules might have an additive or independent role in alterations of the neural development in schizophrenia, especially regarding the insula pathology [38]. Here, DISC1 is linked to schizophrenia.