In this study it was shown an increasing expression of the subunit p65 of NfKB which resulted in increased transcription of vascular cell adhesion.molecule-1 (VCAM-1) and monocyte chemo attractant molecule-1 (MCP-1) in human aortic endothelial cells under hyperglycemia medium [45]. The gene discussed is CCL2; the disease is Hyperglycemia.