NFKB1 and Hyperglycemia: Oxidative-stress is associated with hyperglycemia [45–48], and the existence of other conditions like viruses, some pathogens, and radiation are supposed to phosphorylate IkB resulting in its degradation, liberation and activation of NFkB which translocates to the nucleus to induce the transcription of several molecules related to inflammation, vascular adhesion and migration of monocytes [44].