The degree of dementia in a large DLB cohort (>150 patients), determined longitudinally by a battery of cognitive function tests, was found to be associated with Lewy body pathology and was independent of amyloid and tau pathology 43, while in a small (22 patients) group of DLB patients cortical and subcortical Aβ pathology correlated with the incidence of Lewy bodies, although no clinical measures were described 10. Here, MAPT is linked to Lewy body dementia.