Compared to non-obese diabetic (NOD) mice who develop SS-like symptoms, both IFN-γ and IFN-γ receptor (IFN-γR) gene knockout NOD mice (NOD.IFN-γ-/- & NOD.IFN-γR-/-) showed no subsequent autoimmune response against the salivary glands [16]. The gene discussed is IFNGR1; the disease is synovial sarcoma.