GAA and hydrops fetalis: In an earlier study, we found that RNAi-mediated silencing of an A. aegypti alpha-glucosidase ortholog of a D. melanogaster gene, previously shown to function as a DENV HF in a fly cell line, did not influence the adult mosquito's susceptibility to DENV infection in the Rock, Sin, or PTri strain of A. aegypti[30].